MECHANISM OF ACTION: MOXIFLOXACIN 0.5%
Fluroquinolone antibiotics bind with DNA gyrase enzyme (TOPOISOMERASE 2&4) Essential bacterial enzymes involved in DNA replication thus interfers with bacterial survival.
EFFECTIVE AGAINST: GRAM +VE AEROBIC
1) Staph aureus
2) Staph. Epidermidis
3) Staph. Pneomonea
4) Staph. Viridous
GRAM –VE AEROBIC
1) H. Influenzae
2) H.